If you are exploring fertility treatment options, Preimplantation Genetic Testing (PGT) may be an important consideration. This advanced genetic screening process helps identify chromosomal abnormalities in embryos before implantation, providing valuable insights that can increase the chances of a healthy pregnancy. Whether you are using fresh or frozen embryos, this testing offers flexibility in your reproductive journey.

PGT involves carefully extracting a small number of cells from a developing embryo for genetic analysis. Since this procedure requires embryos to be developed in a controlled laboratory environment, IVF or intracytoplasmic sperm injection (ICSI) is necessary, even if you do not have a history of infertility. The process is a collaboration between highly specialized embryology and genetic testing laboratories. At our fertility center, eggs are fertilized in the lab, and once the embryo reaches the appropriate stage, a small sample of cells is delicately removed. These cells are sent to an off-site genetic laboratory, where they are screened for chromosomal abnormalities. If an embryo is found to have a genetic issue that may impact viability, it is not recommended for transfer. This approach helps optimize the likelihood of a successful pregnancy while reducing the risk of miscarriage or inherited genetic conditions.

PGT-A (Aneuploidy Screening)  is generally recommended if you are 35 or older due to the increased risk of chromosomal abnormalities, such as aneuploidy, which can affect embryo viability and increase the chances of miscarriage. PGT-A helps identify embryos with the correct number of chromosomes, improving implantation rates and reducing the risk of miscarriage or failed IVF cycles. If you have experienced recurrent miscarriages or multiple failed IVF cycles, PGT-A can be beneficial.

If you or your partner carry a known genetic disorder, PGT-M (Monogenic Disorder Screening) can help prevent passing these conditions to your child by identifying embryos unaffected by the specific genetic mutation. It is also useful in cases of severe male infertility, particularly when sperm quality is compromised. It may also be recommended if there are known sperm-related genetic concerns that could affect embryo development.

If you are considering PGT as part of your fertility journey, our team is here to guide you through the process. We understand that each patient’s situation is unique, and we are committed to providing you with the information and support needed to make the best decision for your reproductive future. If you have any questions or would like to discuss whether PGT is right for you, we encourage you to reach out to our fertility specialists.